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The first thing in the human personality that dissolves in alcohol is dignity. 
Author Unknown

Alcoholism

The social problems arising from alcoholism can be massive and are caused in part due to the serious pathological changes induced in the brain from prolonged alcohol misuse and partly because of the the intoxicating effects of alcohol. Being drunk or hung over during work hours can result in loss of employment, which can lead to financial problems including the loss of living quarters. Drinking at inappropriate times, and behavior caused by reduced judgment, can lead to legal consequences, such as criminal charges for drunk driving or public disorder, or civil penalties for tortious behavior. An alcoholic's behavior and mental impairment while drunk can profoundly impact surrounding family and friends, possibly leading to marital conflict and divorce, or contributing to domestic violence. This can contribute to lasting damage to the emotional development of the alcoholic's children, even after they reach adulthood. The alcoholic could suffer from loss of respect from others who may see the problem as self-inflicted and easily avoided. Source: Wikipedia
MayoClinic.com Treatment of Alcoholism | Psych Central 

Alcohol Use Statistics  

Alcohol

Alcoholism Statistics Alcoholism Google Directory 
National Institute on Alcohol Abuse and Alcoholism
Institute of Alcohol Studies Addiction Resource Guide
Alcoholism and Alcohol-Related Problems Down Your Drink
Summary of Effects
Long-term effects of consuming large quantities of alcohol can lead to:
• permanent damage to vital organs
• several different types of cancer
• gastrointestinal irritations, ... nausea, diarrhea, & ulcers 
• malnutrition and nutritional deficiencies
• sexual dysfunctions
• high blood pressure
• lowered resistance to disease

Wikipedia

Alcohol and Health: Short-term effects of alcohol | Long-term effects of alcohol | Alcohol and cardiovascular disease | Alcoholic liver disease | Alcoholic hepatitis | Alcohol and cancer | Alcohol and weight | Fetal alcohol syndrome | Fetal Alcohol Spectrum Disorder | Alcohol consumption and health | Alcoholic lung disease

Yahoo

Fetal Alcohol Syndrome (FAS)@ | Personal Experience | Support Groups